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    Watch list 2017: Top therapeutic areas

     

    Diabetes

    Lassen at Prime Therapeutics calls diabetes the number one nonspecialty drug category, accounting for 13% of the PBM’s total drug spend.

    “The majority of that increase is due to more utilization and inflation,” he says, “but also to new, higher cost brands that are being promoted—an average cost of $300 a month for a combination of oral and injectables compared to $20 for a generic. We want to better understand the data to determine if the much higher costs justify incremental improvement in overall treatment.”

    Some injectibles might be more convenient because they only need to be taken once or twice a week vs. daily oral medications. “But do they improve outcomes?” he asks.

    There is currently no generic insulin available for diabetes.

    Rubin sees diabetes as ripe for advancements in treatment, starting with less stringent warnings from the FDA on using metformin, which is a first-line medication prescribed for type 2 diabetes.

    In December 2015, the FDA approved Basaglar (insulin glargine injection) as a follow-on product to Lantus for treating types 1 and 2 diabetes. Basaglar is the first insulin product approved through an abbreviated approval pathway under the Federal Food, Drug, and Cosmetic Act. It became available in December 2016.

    Chris Peterson, director of emerging therapeutics for Express Scripts, says Basaglar should help bring down the cost of Lantus, providing a negotiation tool with manufacturers.

    Xultophy, a combination of two existing drugs—Victoza (liraglutide), a glucagon-like peptide-1 receptor agonist, and basal insulin Tresiba (insulin degludec), was approved in November 2016. Soliqua 100/33, a combination of Lantus and lixisenatide, was also approved in November. Regardless of price, the once-a-day administration for both might make the drugs more palatable.

    Next: Autoimmune disorders

     

    Mari Edlin
    Mari Edlin is a frequent contributor to Managed Healthcare Executive. She is based in Sonoma, California.

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    • perfectukc@------.com
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    • MIZEXNELSON@------.com
      Happiness is all i see now I never thought that I will be cured from HERPES virus again. I have been suffering from a deadly disease (HERPES) for the past 3 years now, I had spent a lot of money going from one place to another, from churches to churches, hospitals have been my home every day residence. Constant checks up have been my hobby not until this faithful day, I was searching through the internet, I saw a testimony on how DR UDURO helped someone in curing his HERPES disease, quickly I copied his email which is [email protected] just to give him a test I spoke to him, he asked me to do some certain things which I did, he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days, after using the herbal cure, behold I was free from the deadly disease, he only asked me to post the testimony through the whole world, faithfully am doing it now, please BROTHER and SISTER, MOTHER and FATHER he is great, I owe him in return. if you are having a similar problem just email him on [email protected] or you can whatsApp his mobile number on +2348138634433 He can also curu this disease like HIVand AIDS,DIABETICES,HEPATITIS B ABC,CANCER,GONORRHEA,LASSA FEVER,GONORRHEA,MENOPAUSE DISEASE,Many more HE CAN ALSO CAST A SPELL FOR YOU TO BRING BACK YOUR EX LOVER...
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    • perfectukc@------.com
      I Am Here Again To Say A Big Thanks To Dr.Sebi Fori Making Me A Complete woman Again, I Was Infected With Herpes For 5 Years I Have Been Seriously Praying To God And Searching For Cure. I Came Here Last Month To Search For Solution To My Problem And I Saw A Comment Of People Talking About Different Doctors And God Directed Me To Choose Dr.Sebi And I Contacted Him, He Sent Me A Medicine And Directed Me On How I Will Take The Medicine For 7 Days, I Did So And Went For A Test And My Result Came Out As Negative. I Am So Happy, I Shared Tears Of Happiness And I Have Taken It Upon My Self To Always Testify About How God Used Dr.Sebi To Solve My Problem. I Am A Clean woman Now, Without Any Virus If You Are Infected With Any Disease Like HIV, AIDS, CANCER HERPES Or Any Other Disease You Can Also Be Happy Like Me By Contacting Dr Sebi Through His Email: [email protected] Or Whatsapp +2348153863900
    • UBM User
      Unbeleivable that they are still missing the mark on where healthcare should focus resources and it is mental health to include drug and alcohol addiction, depression, bipolar disease, ADHD, ADD. They are repeating the same mistakes because for a high of all these disease processes they are choosing to pour money in research into have their beginnings and cores in the mental health. Obesity for many is sugar addiction, food addiction and obsessive compulsive behavioural disorders. All this will do is bandaid the problem and I doubt if even it does that much good. Causes and conditions need to be the center of these conversations in medical fraternity.
    • UBM User
      Unbeleivable that there is such a focus on the conditions and not the causes. We are still missing the mark on where healthcare should focus resources and it is in mental health to include drug and alcohol addiction, depression, bipolar disease, ADHD, ADD. We are repeating the same mistakes vy not addressing behavioural health because for a high percentage of the disease mentioned are caused from underlying mental health problems. It appears we are choosing to pour money in research of the samne things to no avail. Instead we should pour it into mental health. Obesity for many is sugar addiction, food addiction and obsessive compulsive behavioural disorders. All this will do is bandaid the problem and I doubt if even it does that much good. Causes and conditions need to be the center of these conversations in medical fraternity.
    • essayreviews123@------.com
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